If you’re in perimenopause and you keep getting UTI symptoms — burning, urgency, the constant feeling that you need to go — but your urine culture comes back negative, you’re not imagining it. Declining estrogen during perimenopause causes the tissues of the urethra to thin and lose support, making them far more vulnerable to irritation and inflammation that mimics a UTI without actually being one. In this video Susan Winograd, MSPT, explains exactly what’s happening and what you can do about it.
The tissues of your urethra are highly dependent on estrogen. During perimenopause, as estrogen levels decline, these tissues become thinner and less supported. This makes your urethra more vulnerable to irritation, inflammation, and UTI-like symptoms—even without an actual infection.
But here’s the good news: You don’t have to suffer! There are effective ways to address this.
1. Consider topical estrogen prescribed by your provider to restore tissue health and support.
2. Stay hydrated and avoid bladder irritants like caffeine or spicy foods.”
3. Work on pelvic floor health with a therapist to improve urethral support and reduce irritation.
Taking these steps can make a huge difference in your comfort and bladder health. If you’re experiencing these symptoms, reach out to your provider or a pelvic floor therapist for help.
If UTI-like symptoms are part of a broader picture of perimenopause symptoms — including bladder leaking, pelvic pain, painful sex, or brain fog — our Perimenopause & Menopause Treatment program addresses the full hormonal and pelvic floor picture together. Kelley Maple, APRN, leads comprehensive hormone testing and topical estrogen management alongside Susan’s pelvic floor PT.
TIMESTAMPS
0:00 Are you noticing UTI symptoms during perimenopause?
0:28 Perimenopause leads to a decline in estrogen
0:58 Talk to your provider about topical estrogen
1:24 Make sure you’re hydrated
1:36 Stay away from caffeine, carbonated drinks, alcohol
1:54 Find a good pelvic floor physical therapist

